Search results for " platform" in Articles / App Notes
Article
The New World of Biopharmaceutical Manufacturing
Companies are implementing end-to-end single-use platforms for monoclonal antibody, antibody drug conjugate, and vaccine production. Flexible facilities are likely to become an important part of large…
Article
N-Glycan Analysis of Biotherapeutic Proteins
These new platforms are coupled with software to assist in peak integration, peak calling, and determination of relative abundance, allowing many samples to be processed in a single day. Ease and spee…
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Downstream Processing for Cell-Based Therapies
Current available DSP platforms generally offer either high specificity or high throughput, but rarely both. While highly specific labeling separation systems may be suitable within low volume product…
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Biopharma in 2016: Higher Quality Drugs, Less Expensive Manufacturing
…rned Accelerate Vaccine Development
Overcoming Buffer Challenges With In-Line Conditioning
A Platform Approach to Purification of Antibody Fragments
References
1. Walker, Nigel, Innov…
Article
Design and Qualification of Single-Use Systems
… fitment (leak) integrity properties, sterilizability, drainability, incorporation into an automated platform as the disposable fluid path, etc.
• Manufacturability ensures that the SUT productio…
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Vaccine Development Faces Urgency and Challenges
…urther the development and manufacturing of new Zika vaccine candidates and other innovative vaccine platform technologies. BARDA already is working with Brazilian agencies to develop a Zika vaccine …
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Antibody Production in Microbial Hosts
Glycoengineering platforms, display technologies and library creation, and robust manufacturing process development support the use of microbial cells as suitable candidates for pharmaceutical develop…
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Selecting the Right Viral Clearance Technology
…erally used to understand the clearance potential of a step that will be included in a manufacturing platform.
Lot-to-lot-variation in both product feedstocks and consumables is another factor th…
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Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Bispecific antibodies are also considered an effective platform for the delivery of therapeutic antibodies across the blood-brain barrier (2). This suggests that in certain cases, bispecific antibodie…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
to use its Mobius bioreactor platform to expand and harvest HepRG cells. Cytiva is also evaluating Wave and other systems and set up a center of excellence in Wales recently.
In other equipment ar…