Search results for " platform" in Articles / App Notes
Article
Nurturing Knowledge from Disparate Data Streams
These data are stored and manipulated using a variety of software platforms from different suppliers. Pharmaceutical scientists must be able to integrate and interpret these data in an efficient manne…
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Improving Process-Scale Chromatography
Thermo Fisher has introduced a new platform technology with large-scale production capability based on affinity chromatography resins that address challenges in the purification of mAbs, antibody frag…
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Tackling Analytical Method Development for ADCs
The platform approach
For many small-molecule drugs, a platform of generic screens is often used for drugs based on their structures and mechanism of action. For ADCs, however, it is difficult to …
Article
Cell-free Expression Systems Pose Cell Culture Alternative
…r cell-free expression (7)
• Medicines have been manufactured using on-demand, portable platforms comprised of detoxified lysates that contain endotoxin levels well below those in FDA-approved …
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Remote Monitoring and Big Data Advance Upstream Automation
…ease the speed of the implementation of model-based control at the production scale and available as platform approaches that deliver end-to-end solutions, according to Vann.
Follstad adds that…
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Cytiva and 4Tune Engineering Collaborate on Cell Therapy Quality Risk Management
3, 2020, Cytiva and 4Tune Engineering, a manufacturing-sciences and technology company, announced that they have entered into an agreement to include 4Tune Engineering’s iRISK platform in Cytiva’s cel…
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Design Considerations for a Commercial Cell and Gene Therapy Facility
…uction) and characterized by larger single-use bioreactor skids with large downstream chromatography platforms, often segregated into two or more rooms. In mAb production, Chinese hamster ovary cells…
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Industry Adoption of Single-Use Systems Remains Low
… technologies, including FlexFactory for biologics, a centrally automated, flexible biomanufacturing platform based on single-use technologies, that allows for GMP manufacturing. The acquisition comp…
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Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
This puts mAb purification platforms in a good position to handle future developments in upstream technology. However, although mAbs is still the biggest application area and has significant growth, t…
Article
Fermentation for the Future
The company is currently implementing an automated microbial mini-fermentation system integrated in a robotic platform. The 15-mL bioreactor is based on single-use technology and allows up to 48 paral…