Search results for " method"
Article
Accelerating VLP purification process development
Indeed, a method for the large-scale production of VLPs is production in suspension cell culture, and extracting the VLPs from the cell culture supernatant is a time and labor-intensive process.
…
Article
Principles of Cell Line Development
It also takes a closer look at where it fits into this wider process including:
Overall path to market
Key processes and methods
Tools and equipment
Key regulatory re…
Article
Maximum Output Starts with Optimized Upstream Processing
Development of rapid analytical methods; the use of robust inline, online, and at-line monitoring and testing capabilities to reduce the reliance on end-product testing, exploration of accelerated reg…
Article
Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
We take all of this data, we leave the model to fit the real-world physical parameters, so diffusion rates and porosities with an inverse method. So that simply, we turn out thousands of runs and find…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.
Feliza Mirasol
Among the challenges in upstrea…
Article
Sanitization of AxiChrom™ Columns Packed with Chromatography Resin
This study evaluates sanitization methods based on 1 M sodium hydroxide (NaOH) as sanitization agent using methodology previously developed for peracetic acid (PAA).
Access study data here…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
The current lack of standardization of analytical methods for titer comparison, however, prevents effective assessment of available upstream technologies, according to Tan.
Challenges of working w…
Article
Setting Up Bioprocessing Systems for Digital Transformation
“By generating digital twins based on such approaches, the convoluted behavior of material, system, molecule, and method may be simulated, with the time consuming, expensive, and labor-intensive exper…
Resource
Increase Efficiency with the Right Buffer Management Strategy
There are new buffer preparation methods that can bring significant efficiency improvements over manual preparation while ensuring high quality. This webinar focuses on the sweet spots, advantages, …
Article
WEBINAR ON DEMAND: Increase Efficiency with the Right Buffer Management Strategy
Watch webcast >>
There are new buffer preparation methods that can bring significant efficiency improvements over manual preparation while ensuring high quality. This webinar focuses on the swee…