Search results for " method" in Articles / App Notes
Article
Innovations in Perfusion Bioprocessing
In this study, we present a method for deriving perfusion culture media by leveraging existing fed-batch media and feeds.
Furthermore, we illustrate the successful transfer of the develop…
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In silico optimization of AAV full/empty particle separation with AIEX
Mechanistic modeling is the tool of choice to find the optimal AIEX chromatography method.
We present a guiding workflow showcasing in silico process optimization of full and empty AAV5 particle se…
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
“Most likely, sterile filtration for sufficiently small viruses will remain the method of choice, whereas for larger viruses, use of sterile single-use materials, stringent control of starting materia…
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Life cycle assessment of the protein A process in mAb manufacturing
Life cycle assessment (LCA), a systematic analysis of the environmental impact of a component or process from its material origin to its end-of-life deposition, is a common method for quantifying envi…
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Unraveling the secrets of poloxamer 188 - A webinar mystery
We'll unmask the culprit -- and the RP-LC/MS method we developed to prevent it from striking again!
Watch
Article
A Closer Look at Affinity Ligands
Affinity chromatography is a separation method based on the specific binding interaction between an immobilized affinity ligand and its binding partner. The most common example in the realm of bioproc…
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Unlock UNICORN™ software with a free online course
Refresh on the basics of UNICORN™ software for chromatography systems with this free online course. The course only takes 35 minutes and you will receive a certificate when you finish.
Enr…
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Better bioprocess scaleup with Bioreactor Scaler Pro
Are you still using the manual input, trial-and-error method when scaling your cell culture process, spending long hours in the lab analyzing uncertain data?
With Bioreactor Scaler Pr…
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Benefits of DoE vs mechanistic modeling
You will learn that, quite often, these methods work hand in hand in a hybrid setup to improve your process development!
Watch this webinar on-demand
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Determining and Optimizing Dynamic Binding Capacity
While the same general method is used to determine the DBC for many different biomolecules, matrices, and chromatography operations, all of these variables can influence which process parameters are i…