Search results for " method" in Articles / App Notes
Article
Combining Purification Techniques in a Multistep Approach
With the right combination of different purification techniques, resins used, and how your methods are set up for a multistep approach, your protein purification will be successful in terms of either …
Article
The Challenge of Disruptive Technologies in Bioprocessing
Both methods would remove the challenge originating from practically limited column size or filter membrane area,” he states.
In addition, membrane absorbers have been suggested as a “disruptiv…
Article
Queue Up Your Chromatography Steps
To save time and increase throughput, many scientists consider increasing the level of automation in their protein purification workflows. Learn how you can set up automated multi-step protocols uti…
Article
Challenges in Cell Harvesting Prompt Enhancements
The system uses a hollow spindle technology that provides a method of continuous cell harvesting under hermetic conditions (1).
The system consists of a disk-stack, high-speed separator, pipin…
Article
Miniaturization to Become Even More Successful
The industry has turned to high-throughput process development (HTPD) methods—miniaturization, parallelization and automation in particular—to carry out the large number of experiments required for th…
Article
Understanding Validation and Technical Transfer, Part 2
Does the brewed coffee taste good? How will that be determined? Is it the same as the coffee chosen as a result of the taste testing? Are there any analytical methods that might provide confirmation? …
Article
Understanding Validation and Technical Transfer, Part 3
Testing strategies should be based on analytical method capability, stability, in-process control, and validation results. ICH Q9 provides a comprehensive discussion of quality risk management and ris…
Article
Putting Viral Clearance Capabilities to the Test
Process understanding and careful assessment of risks are essential in developing viral clearance programs.
By Rita C. Peters
nobeastsofierce/Shutterstock.com
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Article
Biopharma Says It Has an Evolution in New Technologies and Processes
Now that several drugs manufactured via continuous processing have been approved, the interest in this processing method has increased significantly.
Q: Can biologic-based drug developers learn an…
Article
Flow Accuracy and Gradient Performance of ÄKTA pilot 600 Chromatography System
A comparable flow accuracy between scales can facilitate scaling of your methods.
In this application note, we demonstrate the flow and gradient formation of the ÄKTA pilot 600 chromatograph…