Search results for " scaling" in Articles / App Notes
Article
Flexible Facilities for Viral Vector Manufacturing
Single-use and modular systems will meet demand for rapid implementation at different scales.
By Jennifer Markarian
Industry experts have noted that there are limitations in the…
Article
Biopharma Seeks Balance
Biopharma Seeks Balance
Biopharma companies can balance competing demands from patients, investors, and regulators by keeping a focus on science.
By Rita C. Peters
…
Article
Remote Monitoring and Big Data Advance Upstream Automation
Connected, integrated bioprocessing enterprises with greater data analytics capabilities are coming.
By Cynthia A. Challener
As upstream processing drives toward higher efficiencies in meeti…
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
The commercialization of cell and gene therapies has become a reality, prompting deeper considerations of logistics, technology, and design for manufacturing facilities.
By Feliza Mirasol
…
Article
Process Chromatography Selection for Downstream Processing Applications
Process Scale-Up
BioPharm: What are some challenges companies may face when scaling-up process chromatography for downstream processing? How might you address these challenges?
Levison (Pall):…
Article
Maximum Output Starts with Optimized Upstream Processing
Developing and scaling up manufacturing operations and analytical testing capabilities are, however, requiring major innovation and the courage to move away from conventional constructs, asserts Botto…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Cell-free expression is promising in preclinical applications, but still presents challenges to scale up for commercial production.
Feliza Mirasol
Among the challenges in upstrea…
Article
A Plastic Pipeline for Commercial Bioprocessing?
For certain volumes, it makes sense to “scale out” versus scaling up, says Bagshaw. Instead of scaling from a 2000-L bioreactor to a 15,000-L bioreactor, a process can go from one 2000-L bioreactor us…
Article
Modeling Bioreactor Performance
…rize their systems, potentially in collaboration with their customers, and develop better models for scaling.
Clapp also stresses that off-the-shelf products only provide the engine for modeling;…
Article
Use of Multivariate Data Analysis in Bioprocessing
Apr 06, 2015
By Anurag S. Rathore, Sumit K. Singh
BioPharm International
The ever increasing demand of biotherapeutics, together with the pressure to contain healthcare costs have motiva…