Search results for "downstream"
Article
Single-Use Workflow for Recovery of a Domain Antibody from E. coli Culture Feed in an Automated Manner
This application note demonstrates the performance of the automated ÄKTA™ readyflux single-use filtration system in microfiltration applications. Here, a domain antibody (dAb) expressed in E. col…
Article
Platform Technologies Improve Protein Expression
Platform technologies facilitate development and accelerate commercialization of protein therapeutics.
By Cynthia A. Challener
Speed to market is essential in the biopharmaceutica…
Article
Tips for Purification Method Editing: Learnings from the Webinar
During the ÄKTA club webinar, “Tips for Protein Purification Method Editing in UNICORN software,” the basics of the UNICORN 7 software were presented. Useful tips and features were demonstrated, …
Article
Work from Anywhere and Add Flexibility to Protein Purification Workflows
The protein purifier of today has a full agenda and many different tasks to perform. It can be difficult to find time for attending full runs in the lab. And when there is time, it might be a challe…
Article
Protein Purification Handbooks
Make sure you have the latest protein purification handbooks!
Whether you are a beginner or an expert, Cytiva handbooks provide practical tips and in-depth information about protein purif…
Article
How to Address Bioburden Challenges: Insights and Tips
Bioburden control is an area of serious concern for anyone making mAbs or other biologicals. Manufacturers’ efforts to avoid microbial contamination are today being complemented by developments from…
Article
Tips for Successful Immunoprecipitation
For immunoprecipitation (IP), there are four main components that you can control to get good results: protocol, resin, format, and antibody. Read these tips to get it right from the start.
Ac…
Article
Column Selection Guide for ÄKTA Systems
Use this guide to facilitate your selection of prepacked chromatography columns.
The guide includes an overview table that shows compatibility of prepacked column formats and ÄKTA syst…
Article
Will My Buffers Work When Using an Inline Conditioning System?
Buffer preparation can be both time and space consuming and can easily become a challenge in biomanufacturing. In-line preparation of buffers from highly concentrated, single-component stock soluti…
Article
Asked and Answered: Your Questions on Ion-Exchange Chromatography
On May 17, 2017, Marianne Carlsson presented the webinar, “Tips for Successful Ion Exchange Chromatography.” After the webinar, Marianne and a panel of R&D scientists participated in a live questio…