Search results for " efficiency"
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Free eBook: Considerations for smarter and faster process development
Biopharmaceutical Process Development -
Considerations for Smarter and Faster Process Development.
What you will learn:
Industry drivers to go smarter and faster in process de…
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Optimizing capture and polishing steps in an rAAV purification process
In this article, we show how we developed an efficient purification process for recombinant AAV (rAAV). The chromatography purification described includes affinity capture to maxi…
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Cell-free Expression Systems Pose Cell Culture Alternative
During a short period of time, the system can make protein biologics with high efficiency with minimal by-products, and you don’t have to worry about proteolytic of recombinant protein caused by prote…
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Innovative Chromatography Resins Can Improve Purity and Quality
By: Feliza Mirasol
Recent innovations in chromatography resins offer promising advantages in downstream bioprocessing.
With ongoing efforts to increase monoclonal antibody (mAb) productivi…
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Eliminating Residual Impurities Starts with a Strategic Plan
Monitoring the efficiency of the residual impurities will be guaranteed through the development of robust analytical methods,” he explains. Savoy also recommends that methods be developed following an…
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Gene Therapies Push Viral Vector Production
Compared to adenovirus and AAV, retrovirus-based vectors show relatively low transduction efficiency in-vivo, but their advantage lies in their ability to integrate stably and confer long-term transge…
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New Therapies Present Scaling Challenges
New Therapies Present Scaling Challenges
Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether processes should be scaled up, scaled out, or use an al…
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Four Steps Toward End-to-End Connected Manufacturing
Reduce costs and increase efficiencies by implementing continuous biomanufacturing strategies into upcoming processes. Continuous biomanufacturing is a key step toward promoting drug quality and imp…
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Advances in Engineering of Protein-Based APIs
Advances in Engineering of Protein-Based APIs
New platform technologies, advanced modeling tools, and addressing patient needs are important developments.
By Cynthia A. Challener
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Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
… benefits in the production of biopharmaceuticals and biosimilars, including cost savings, increased efficiency, accelerated development, production flexibility, and more. Clearly, industry members (…