Search results for " efficiency"
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From cells to purified capsids: How to develop a scalable rAAV process
Adeno-associated virus (AAV) is the most common vector for gene therapy, yet there’s much room to improve production, purification, and analytics. In this webinar we present the latest upd…
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Assessing leachables risk over a complete single-use, mAb process
Single-use systems (SUS) in biopharmaceutical manufacturing give advantages such as improved flexibility and plant efficiency, but also raise concern for compounds leaching from the pol…
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Accelerating VLP purification process development
See how using mechanistic modeling can speed up the purification process development of virus-like particles (VLPs).
Indeed, a method for the large-scale production of VLPs is produ…
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Moving beyond automation - next industrial revolution is digital
Connected machines and software systems can enhance the human workforce, minimize maintenance downtime and spare part inventory for process equipment with the aim to improve process robustness and eff…
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Pandemic Alters Policies and Practices for Drug Development and Regulation
By Jill Wechsler
The need for medicines to combat COVID-19 has impacted the way regulatory agencies carry out their operations.
Drug development and regulati…
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Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator Bioscience AB develops antibody-based pharmaceuticals for cancer treatment, specializing in mono- and bispecific antibodies for tumor-directed immunotherapies. Alligator and Cytiva devel…
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Scalable AAV Production Process for Gene Therapy
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Viral vectors are often used for gene transfer of specific tissue- or cell-type modifications. Several viruses have been investigated for use in cell and gene therapy; adeno-associ…
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Improving Productivity During Process Development and Scaling of Your Process
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Click here to view more Industry Leader Q&As >>
Andreas Castan, PhD, Strategic Technology Partnerships Leader of Business Development & Strategy at Cytiva, provides helpful insig…
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Using Digital Twins to Model Process Chromatography
Models are typically calibrated using lab-scale data for material and cost efficiency, with the model then scaled to predict manufacturing scale by accounting and simulating changes to scale, operatio…
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Track-and-Trace Progress Benefits Supply-Chain Security Efforts
…ions, and regulatory agencies to help advance track-and-trace implementations and drive supply-chain efficiency.
“[In the US,] we have been supporting the [pharmaceutical] industry for the final …