Search results for " media" in Articles / App Notes
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Developing a Continuous Large-Scale Perfusion Cell Culture Process
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Perfusion processes enable continuous operation over extended periods of time by constantly providing fresh nutrients for the cells and simultaneously removing spent…
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Cytiva Invests $500 Million Over 5 Years to Expand Global Capacity
Cell culture media production will increase as the result of new manufacturing lines, cleanroom space, personnel, and additional personnel shifts at the company’s site in Logan, UT. Further, the compa…
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Considerations for Optimizing Process Development
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Intensify your cell culture processes to keep pace with today’s industry and regulatory expectations.
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Gene Therapies Push Viral Vector Production
In addition, it is important to maintain AAV vector biological activity when removing impurities and contaminates present in a feedstock that originates from host cells or culture media. Next to this,…
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Best Practices for Selecting a Top-Quality Cell Line
“This high level of productivity must also be maintained for more than 60 generations at the high-density and in the defined media conditions of large-scale manufacturing,” he says. In addition, the p…
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Ensuring Viral Safety of Viral Vaccines and Vectors
This technique has been applied to treat raw materials such as cell-culture media (21) and glucose (22). The impact of HTST on the properties of treated raw material and the performance of cell-cultur…
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The New World of Biopharmaceutical Manufacturing
…er the past 40 years, single-use systems have moved from simple blood and intravenous bags to simple media and serum containers, and to highly engineered, complex devices that are now mainstream tech…
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Hybrid Bioprocessing: A Q&A with Andrew Sinclair
Where the productivity of the cell line is equivalent in fed batch and perfusion, then the balance favors fed batch based on efficient media utilization and easier development. Perfusion has potential…
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Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
Essential Pharmaceuticals provides an animal-component free media that boosts titer and enhances protein quality. It can be difficult to change or improve processes with the strict regulations around …
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Single-use Bioreactors Have Reached the Big Time
Cytiva has invested heavily in its process development capabilities to help optimize cell-line performance, cell-culture media and supplement consumption, and biologic quality in a continuous process.…