Search results for " small-scale"
Article
Improving the Oligonucleotide Synthesis Experience
Addressing this challenge was one of Cytiva’s main goals when we set out to develop a system for small-scale synthesis and process development.
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Article
Maximum Output Starts with Optimized Upstream Processing
“Efforts have targeted the development of new expression technologies, parallel tracking of activities that are not on the critical path, and implementing high-throughput, small-scale technologies,” c…
Article
Gene Therapies Push Viral Vector Production
“We must bring robust, scalable, industrialized manufacturing processes as fast as possible (less manual and more automated processes) and GMP solutions for both small-scale and large-scale production…
Article
Scalable ADCF Virus Production Using HyClone™ VaccineXpress Medium
In this study, HyClone VaccineXpress cell culture medium was used for the propagation of influenza virus and rotavirus in an animal-derived component-free (ADCF) process. Small-scale microcarrier cu…
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
The commercialization of cell and gene therapies has become a reality, prompting deeper considerations of logistics, technology, and design for manufacturing facilities.
By Feliza Mirasol
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Article
New Guide for Packing HiScale, XK, and Tricorn Columns
This guide summarizes parameters for packing small-scale HiScale™, XK, and Tricorn™ columns with Capto and MabSelect resins from Cytiva.
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Article
Achieving Process Balance with Perfusion Bioreactors
While the implications of media consumption from an economic perspective can be determined at small-scale rather effectively, it is in the scale-up phase where the system design is imperative for real…
Article
Scaling Up Novel Therapies
Cell culture improvements were followed closely by small-scale single-use technologies. As a result, on the bacterial side, developers can now go into production using 100- to 300-L single-use reactor…
Article
Biopharma Says It Has an Evolution in New Technologies and Processes
Exhibitors announced new chromatography systems for pilot- and small-scale production, new resins, mixing systems, kits for glycan analysis and mycoplasma detection, filters, and sensors.
As bi…
Poster
Rapid Process Development of a CIEX Step for a Biosimilar
HTPD experiments were performed in both in 96-well plates and small-scale columns.