Search results for "chromatography"
Article
2014 Manufacturing Trends and Outlook
Ion-exchange chromatography was the most frequently reported (71.6%) followed by chromatography with other resins (62.7%), chromatography with Protein A (56.7%), and membrane-based filters (53.7%).
…
Article
Extractables in Single-Use Systems Used in ADC Manufacturing, Part 2
We performed extractables studies on single-use chromatography and tangential flow filtration systems using common solvents in ADC manufacturing, DMA and DMSO. The low levels of extractables f…
Article
Top challenges in recombinant protein purification process development
Well, for recombinant proteins, you often don't have an affinity solution, an affinity chromatography solution that can be used, which is very different from mAbs, which do have a great affinity solut…
Article
Master the basics of UNICORN™ method editing with a free online course
This free interactive course explains how to create and edit methods in
UNICORN™ software for ÄKTA™ chromatography systems.
Review the basics and learn how to use predefined phases…
Article
Unlock UNICORN™ software with a free online course
Refresh on the basics of UNICORN™ software for chromatography systems with this free online course. The course only takes 35 minutes and you will receive a certificate when you finish.
Enr…
Article
Virus-like Particles as Therapeutic Moieties of the Future
Reverse phase–high-performance liquid chromatography (RP–HPLC) is a frequently used analytical tool for protein characterization and purification, and has been recently shown to be useful for characte…
Article
Cleaning Protein A Resins with 1 M NaOH
In this application note, resistance to high concentrations of NaOH is evaluated in protein A chromatography resins.
Download application note
For more information, visit MabSelect Protein A re…
Article
Column Selection Guide for ÄKTA Systems
… Technical data to help you make your choice
Download the Selection Guide for Prepacked Chromatography Columns
Download the Selection Guide for Size Exclusion Chromatography Columns and Re…
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Compared with conventional chromatography, using stainless steel columns, the use of ReadyToProcess Adsorber membranes can help reduce capital investment, consumption of buffers and other process liqu…
Article
Development of column packing methods based on pressure flow measurements
A typical problem to be addressed during scaleup is the loss of wall support for the chromatography resin as a result of the large change in aspect ratio, causing larger compression of the resin and a…