Search results for " process"
Article
A Look into Biologic Scale-Up Strategies
To maximize cell-culture output, strategy is required that takes into consideration factors such as cell culture media, environmental monitoring, and process controls. Yet, despite decades of process …
Article
Mechanistic modeling quiz: Test your knowledge
The benefit of in silico process development based on a mechanistic model? You can test thousands of purification options in a few hours.
How well do you know mechanistic chromatography modeling? …
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Better bioprocess scaleup with Bioreactor Scaler Pro
Are you still using the manual input, trial-and-error method when scaling your cell culture process, spending long hours in the lab analyzing uncertain data?
With Bioreactor Scaler Pr…
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How to program, run and evaluate a design of experiments (DoE)
Martin Sichting, Product Manager Lab Scale Chromatography Systems at Cytiva, guides you through the DoE process.
You’ll learn how to program, run, and evaluate a design of experiments (DoE) run. An…
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Webinar: Optimizing a HIC step with HTPD
This workflow includes the use of high-throughput process development (HTPD) plates to facilitate the choice of resin and initial conditions for column chromatography, and a design of experiments (DoE…
Article
Good Modeling Practice
Mechanistic models have become a very promising technique to describe chromatography processes. These models offer numerous advantages such as cost and time reduction and are applicable at any point o…
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Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
…
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FAQ: Scale-up and scale-down with mechanistic modeling
A mechanistic model can simplify your process development projects. The model eases scale-up and scale-down between lab scale and production scale. To apply model-based scale-up and scale-down…
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Moving beyond automation - next industrial revolution is digital
Connected machines and software systems can enhance the human workforce, minimize maintenance downtime and spare part inventory for process equipment with the aim to improve process robustness and eff…
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Pandemic Alters Policies and Practices for Drug Development and Regulation
An important innovation was FDA’s expanded use of the Emergency Use Authorization (EUA) process to speed successful products to patients during the health emergency. At the same time, the regulators r…