Search results for " process"
Article
Contract Manufacturing Through the Years
… as the global bio/pharma companies had large internal laboratories and manufacturing facilities for process development and commercial production. There wasn’t a biologics contract manufacturing sec…
Poster
Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
In this application note, the effects of treating MabSelect SuRe protein A affinity resin with 20 mM PAA every fourth process cycle for more than 100 cycles were investigated. The results show that t…
Article
Extractables Studies for Single Use Systems Used in ADC Manufacturing, Part 1
The use of organic solvents in the ADC process might , however, raise questions about potential leachables from the plastic and elastomeric materials of single‑use components. To address those conce…
Article
Efficient purification of meningococcal polysaccharides in a two-step chromatography workflow
The described process constitutes a viable alternative to the traditional process for purification of meningococcal polysaccharides to eliminate the need for time-consuming phenol extraction steps. …
Article
Efficient Purification of Pneumococcal Polysaccharides in a Chromatography Workflow
The described process constitutes a viable alternative to the traditional process for purification of pneumococcal polysaccharides to eliminate the need for phenol extraction, while increasing process…
Article
Technology solutions simplifying chromatography unit operations
While each of the aforementioned steps can potentially be time-consuming and have significant effect on overall process performance, there are many tools available from Cytiva that address the challen…
Article
Make buffer preparation more time and cost efficient with inline conditioning
GE's extensive HyClone™ buffer and process liquids portfolio include stock solutions suitable for in-line conditioning. Both standard formulations and customized solutions are available.
To learn …
Article
Principles and methods for automated multistep protein purification
Read principles Q&A blog post
Methods of Automated Multistep Protein Purification
Summarized questions related to methods of multistep processing.
Read methods Q&A blog post
Article
Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
By eliminating this concern, you can focus on the core process.
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Poster
Modes of controlling charge variant distribution in Mab production
Charge variant distribution is a critical quality attribute for MAbs and is therefore of interest to monitor and control during the production process. In this study, we investigated the effects of ce…