Search results for " process" in Articles / App Notes
Article
Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
Fibro PrismA is a new protein A fiber chromatography format developed to complement traditional resin-based chromatography. The protein A fiber matrix has an open pore structure in which mass transf…
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Addressing mAb Purification Bottlenecks with Rapid Cycling Chromatography
The rapid purification enables higher throughput in research and process development, and the technology opens up new opportunities for cost efficient single-use chromatography in large-scale commerci…
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Manufacturing of Vaccines and Viral Vectors
However, the challenge not only lies in developing a vaccine but also in the ability to scale up the manufacturing process.
In this article, general guidelines for scaling up a viral vector and vi…
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Getting Ahead of the Game in Cell and Gene Therapy
Here, we present an article based on an interview with Carol Knevelman, Vice President, Head of Process R&D at Oxford Biomedica, who shared a case study on large-scale lentiviral vector production at …
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Mechanistic Modeling of Chromatography: Opportunities and Challenges
Explore opportunities and challenges of an approach that can help make process development become faster, more scientific, and more reliable.
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Automated Buffer Preparation – Increasing Production Capacity While Maintaining Footprint
In fact, buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing, as large volumes of buffers and process liquids are often required as production capacity …
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A Diverse Landscape of Patent Issues Seen in the US, UK, and the EU
… they are outside the protection of expired product patents, so most of the litigation has been over process patents for drug production. This situation is expected to change (but not in the short te…
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Upstream PD Time-Saver: Optimize Early
Identify the right combination of culture medium, feed supplements, and feeding strategy early in upstream process development to conserve precious time and resources.
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Case Study: Oncolytic Adenovirus Production
This case study describes a robust upstream process and downstream process for oncolytic adenovirus production. Purity of final samples meets regulatory requirements.
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Article
Jefferson Institute for Bioprocessing Opens Near Philadelphia, PA
According to the press release, JIB offers a range of training programs to advance the skills and knowledge of scientists, engineers, and technicians who work in process development and biomanufacturi…