Search results for " modular" in Articles / App Notes
Article
Roadmap Leads to Innovative Biomanufacturing Strategies
One of the manufacturing scenarios we determined would be increasingly relevant was mobile and modular facilities. Such smaller scale and portable facilities will increasingly gain importance for deli…
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Being Thorough When Transferring Technology
This means modular thinking and standardization can ease tech transfers. An important aspect of many of these processes is the human element, which is often a larger consideration than it is even for …
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Automating Bioprocesses
Automation of stainless-steel systems and single-use systems differs in complexity.
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used st…
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Managing Biomanufacturing Capacity Expectations
BioPlan found that the development of more efficient single-use products, better downstream purification technologies, the introduction of continuous downstream operations, and increased modularizatio…
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Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Surface plasmon resonance is helping define bispecific antibodies, the next-generation of biopharma therapeutics.
By Robert Karlsson
Abstract
Biotherapeutic antibodies are still the larg…
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Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Dynamic binding capacity (DBC) was assessed using high-throughput modular mini-columns (Cytiva). By using mini-columns operated in parallel, a larger number of different experimental conditions, such …
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Biomanufacturing Outsourcing Globalization Continues
For example, Cytiva built two facilities in China for CMO JHL Biotech, including a KUBio modular biopharma factory in Wuhan that will house 2000-L single-use bioreactors (4). Pall Corp. opened its Lif…
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Continuous Manufacturing: A Changing Processing Paradigm
The company’s continuous “Next-Generation Biomanufacturing Facility” uses single-use bioreactors, disposable plastic containers, real-time quality analysis, and also boasts modular design. It is expec…
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Application of Quality by Design to Viral Safety
There will be instances when the design-space concept may intersect with the development of modular viral clearance claims. For companies with robust pipelines using closely related manufacturing meth…
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EMA Invites Comments on New Guidance for Vaccine Development
The new modular guideline is intended to cover and update in one single, consolidated document the existing guidance on regulatory, quality, non-clinical and clinical aspects of the development of all…