Search results for " microcarrier"
Article
Mapping a Route for Cell and Gene Therapy Process Development
While cell and gene therapies differ in many ways, some of the best practices for process development and validation are similar.
By Cynthia A. Challener
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Article
Scaling Up Novel Therapies
Scaling Up Novel Therapies
Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies?
By Agnes S…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
One alternative is to scale up the production on microcarriers. Another solution is to use suspension-adapted cells, which can facilitate scale-up possibilities. In this work we demonstrate an effici…
Article
Reconciling Sensor Communication Gaps
Where anchorage-dependent cells confound optical methods, permittivity easily quantifies them because the microcarriers are coulombically inert.cleaning validation, and calibration.
“You can also …
Article
Modeling Bioreactor Performance
“CFD modeling is used to understand the shear forces in the different regions of a bioreactor, particularly those close to the stirrer, to predict if the bioreactor design will maintain the microcarri…
Article
Trends in Single-use Bioreactors
Eppendorf’s BioBLU single-use vessels have the ability to run continuous processes for both suspension cells and adherent cells whether customers are using microcarriers or a packed bed with Fibra-Cel…