Search results for " HTS"
Article
Addressing the Challenges in Downstream Processing Today and Tomorrow
The HTS method has also been applied to the development of other purification processes for unique biotherapeutic modalities where screening of a large number of resins may be required.
Another cons…
Article
DoE Provides Benefits, but Preparation Is Necessary
Even with the use of HTS, however, implementation of DoE for formulation development can be time consuming and resource intensive and can translate into more extensive experimentation than planned, ac…
Article
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
A major advantage of SPR-based analysis is its ability to estimate the association and dissociation rate constants, an …
Article
Miniaturization to Become Even More Successful
Industrial bioprocess development has changed significantly in the last decade, driven primarily by two major factors: ever-rising R&D costs of developing therapeutic candidates with simultaneous de…
Article
High-Throughput Process Development in an Historical Environment
As an example of their utilization, Chris Daniels from Merck presented work with design and commissioning of a BSL-2 HTS platform for process development of viral vaccine production, where all liquid …