Search results for " recombinant"
Article
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
By Luhong He, Christopher Frye
Abstract
The Chinese hamster ovary (CHO) cell lines used for the production of recombinant therapeutic proteins are immortalized cells with a relatively high degre…
Article
Top challenges in recombinant protein purification process development
I'm really looking forward to this discussion today on recombinant protein purification process development.
In the industry, we're seeing recombinant proteins more often, right? And we're seeing …
Article
Webinar about a new affinity chromatography technology for recombinant proteins
• Process developers who need faster and smarter ways to develop processes for recombinant proteins that don’t have an affinity binding partner.
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Article
Insights from process developers - top challenges in recombinant protein purification
In this article, we focus on the challenges in purifying recombinant proteins that lack affinity chromatography solutions.
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Article
From Darwin to Recombinant Fc Multimers
…QbD approach, delivered a robust process control strategy to deliver a high-level purity and quality recombinant VIIa (rhFVIIa) from a somewhat unusual expression system: milk of transgenic rabbits. …
Article
Video: Standardize recombinant protein purification process development
Cytiva™ Protein Select™ resin is an affinity chromatography resin for purifying recombinant proteins using the self-cleaving Cytiva Protein Select tag. During an affinity step performed with C…
Article
Production of recombinant proteins using a novel affinity technology
This scientific paper from Journal of Chromatography A describes results of a study utilizing a Cytiva Protein Select™ affinity resin and tag platform to produce any recombinant proteins.
Re…
Article
Recombinant Adeno-Associated Virus Type 5 Production Process
A scalable recombinant adeno-associated virus (rAAV) type 5 production process was developed using transfected HEK293 suspension cells.
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Article
Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
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Article
Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells
As of March 2020, more than 4310 gene therapy clinical trials have been performed worldwide, with only 518 of them in Phase III and Phase IV. As the gene therapy projects enter clinical Phase III or g…