Search results for " purification" in Articles / App Notes

Article Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator and Cytiva developed an efficient downstream purification process for a cancer immunotherapy bispecific antibody (bsAb).  Read more

Article Improving Capacity in DNA Plasmid Purification
Working with plasmids? Plasmid supply is in high demand these days. Join Tony Hitchcock on May 6, 2020 to learn more about this critical market and how Cobra Biologics is working with Cytiva …

Article Purification of Plasmid DNA
Plasmid DNA is the building block of advanced therapies. As these therapies take off, so does manufacturing demand. By switching to modern chromatography resins, Cobra Biologics was able to increase…

Article Quality by Design in Biotherapeutics Purification: Understanding and Addressing Sources of Process Variability
This white paper summarizes information around resin variability, serving as a reference and providing support for developing robust purification processes for biopharmaceuticals.

Article Bispecific Antibody Purification: Insights and Case Studies
For purification, there’s not just one right answer to which strategy to use. Here are some industry insights to help you navigate the bispecific jungle. Read Article

Article Developing an Efficient Adenovirus Downstream Purification Process
This application note describes the development of downstream chromatography steps for purification of adenovirus from HEK293 cell culture harvest. To read the application note click her…

Article Optimization of Adenovirus Midstream Purification Steps
In this application note, studies of midstream purification steps in an adenovirus production process is performed. Based on the results, suggestions for the choice of consumables and conditions for v…

Article Freedom to Roam During Protein Purification Runs
Have you ever felt tied to your ÄKTA system and itching to get out of the lab? Consider this scenario: You have started a run in the lab and want to get some work done in your office. You may …

Article Handbook: Design of Experiments in Protein Production and Purification
Design of experiments (DoE) is a technique for planning experiments and analyzing the information obtained. The technique allows us to use a minimum number of experiments, in which we systematically v…

Article Optimize Column Loading Strategy to Gain Productivity in Protein Purification
Are you looking for a way to improve productivity in your affinity chromatography step? Have you ever applied the concept of variable loading to gain productivity? By varying residence time (RT) ove…

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