Search results for " production" in Articles / App Notes
Article
Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Surface plasmon resonance is helping define bispecific antibodies, the next-generation of biopharma therapeutics.
By Robert Karlsson
Abstract
Biotherapeutic antibodies are still the larg…
Article
Novel Vaccine Technologies Meet the Need for Pandemic and Therapeutic Solutions
As a result, there is an urgent need to develop alternative vaccine production methods that can either generate large quantities of vaccines in a much shorter time and/or produce more broadly effectiv…
Article
Moving Biosimilars Forward in a Hesitant Market
The biosimilars landscape is growing as market factors, such as pricing pressure, advanced bioprocessing and analytical technologies, and upcoming patent expirations for innovator biologics dr…
Article
Virus-like Particles as Therapeutic Moieties of the Future
At least 110 VLPs have been constructed so far from 30 different virus families (1), and a variety of expression systems ranging from bacteria to mammalian cell systems have been used for their produc…
Article
Eliminating Residual Impurities Starts with a Strategic Plan
It does require, however, a thorough understanding of the process combined with appropriate control strategies to minimize the impurities that may be present at the end of the production process (drug…
Article
Driving Improved Access to Biosimilars
Driving Improved Access to Biosimilars
New guidance from FDA, including standards for interchangeability, is expected to speed development of biosimilars, but experts warn against oversimplifying ri…
Article
Getting a Handle on Biopharma’s Most Critical Quality Attributes and Quality Control
So far, however, research has found that full-out production mode offers a better business case for embracing RTR, as does the potential for using a validated approach for another new product if yield…
Article
Modeling the Degradation of mAb Therapeutics
This article in the Elements of Biopharmaceutical Production discusses the kinetics of these degradation pathways as well as the insights they reveal that can help developers ensure the stability of b…
Article
Modern Manufacturing Key to More Effective Vaccines
By Jill Wechsler
A lethal influenza outbreak this past winter has spotlighted the importance of improving and accelerating vaccine discovery and production. Reports that this year…
Article
Single-use Bioreactors Have Reached the Big Time
Significant advances in film technologies, bioreactor designs, stirring mechanisms, and sensor systems have contributed to the increasing adoption of disposable reactors from the lab to production sca…