Search results for "Biomanufacturing"
Poster
Scaling In-Line Buffer Preparation from Process Development to Manufacturing
At the same time, process changes in biomanufacturing require downscaling models. This poster demonstrates how ÄKTA™ avant can be used to replicate the BioProcess™ IC System in bench scale.
Article
Getting a Handle on Biopharma’s Most Critical Quality Attributes and Quality Control
As part of the BioPhorum Operations Group’s (BPOG’s) Biomanufacturing Technology Roadmap, biopharmaceutical manufacturers and technology providers are developing methods that incorporate PAT to see …
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
…ailable to manufacturers, and to examine ways to reduce the number of processing steps required for biomanufacturing, by linking steps to improve process efficiencies. For example, the ability to use…
Article
Case Study: Process for Production of Oncolytic Adenovirus
The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in developing scalable and cost-efficient manufacturing processes. Here…
Article
New Column for Scale-Down Studies
Their dimensions—narrow 10 mm inner diameter, combined with 20 cm bed height typically used in biomanufacturing—make these columns suitable for scale-down studies such as viral clearance studies.
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Article
Experience Compact Scalability
Cost and speed are critical components in biomanufacturing. Can you get a good balance between these two things for your purification tasks, whether you are developing a process or manufacturing at pi…
Article
The Outlook for CMO Outsourcing in 2019
Figure 2: Country selections as destination for international outsourcing of biomanufacturing. (Figure courtesy of the authors)
Despite these industry expectations of more outsourcing to China,…
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
Such was the viewpoint of one popular article, which explored some stumbling blocks to wider spread adoption of single-use systems in the biomanufacturing arena and how capacity needs are changing. …
Article
A Look at the Affinity Chromatography Landscape
Nanofibers for affinity chromatography
A number of different technologies are being explored as supports for affinity chromatography in biomanufacturing. One that is receiving significant attentio…
Article
Scaling Up Novel Therapies
Scaling Up Novel Therapies
Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies?
By Agnes S…