Search results for " DoE" in Articles / App Notes
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Selected courses from cell culture and downstream process development to scale-up and manufacturing
Develop your skills and those of your teams with training courses designed for researchers, process development scientists, engineers, and manufacturing operators.
Built upon our expertise…
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Process Development for Viral Vectors
Scaling viral vector processes can be challenging, but it doesn't have to slow you down. Cytiva can help you own your process and gain valuable expertise. Download a case study from Fast Trak™…
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Developing a HIC polishing step for removal of mAb aggregates
This article describes the development of a flow-through (FT) polishing step using hydrophobic interaction chromatography (HIC) to remove mAb aggregates.
It includes:
- The use of HTPD plate…
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Webinar: Optimizing a HIC step with HTPD
Webinar date: Wed, Mar 8, 2023 11:00 AM EST (5:00 PM CET)
This webinar discusses a step-by-step workflow for optimizing a hydrophobic interaction chromatography (HIC) step.
Thi…
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How Well Do You Know Process Development?
HTPD. DoE. Process understanding. Check your mastery of these and other essential terms by taking this quick quiz.
TAKE THE QUIZ >>
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Report from the 12th Plasma Product Biotechnology Forum
In this case study a normal DoE approach was deemed too challenging due to the high number of different starting materials resulting in an extremely high number of experiments. Such limitations were e…
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Accelerating VLP purification process development
See how using mechanistic modeling can speed up the purification process development of virus-like particles (VLPs).
Indeed, a method for the large-scale production of VLPs is produ…
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Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
Ideally, you want everything smooth and running right down the middle of your intended process parameters, but if something doesn't go that way, it shows up in the trends of the process analytical tec…
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Regulatory Requirements for Safe and Efficient Biologic Drug Development
What does a quality unit entail? It's just not two guys and a bunch of standard operating procedures. There’s a lot more to it than that. I've seen that being a big stumbling block for some companies.…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By establishing effective management of data and knowledge, it will be possible to employ advances, such as artificial intelligence and synthetic biology, to their full potential in upstream bioproc…