Search results for "column" in Articles / App Notes
Article
Tools and Processes for Mature and Emerging Therapies
…g platforms, added options for upstream and downstream systems, and introduced equipment, supplies, columns, media, buffers, single-use systems, and ancillary equipment to promote process capabilitie…
Article
Case Study: Virus Reduction of an Affinity Capture Step
In this study, the virus reduction of an affinity capture step was evaluated in a scale-down column format. The study was performed by a third-party viral testing laboratory in collaboration with a bi…
Article
How To Interpret Protein Binding Capacity: Chromatography Resins
The comparison between protein binding capacities of resin from different suppliers is not always straightforward. Different methods may have to be used, and often these methods are not stated direc…
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Analytical SEC: How Does Back Pressure Relate to Resolution?
High resolution in HPLC is not achieved by applying back pressure to the column. Let’s straighten out what really helps you achieve high-resolution analytical SEC data.
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Article
Protein Analysis with Size Exclusion Chromatography
This white paper presents fundamentals about analytical SEC and describes how our new-generation agarose-based SEC columns are used in analysis of biomolecules.
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Article
Reduce Hands-On Time in Your Ion Exchange Chromatography Runs
Optimization and improvements in ion exchange chromatography can be time consuming. Luckily, there are several tools that greatly facilitate this. Explore four valuable tips for reducing IEX hands-on …
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Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…ines
• Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
• Optimization of Fed‑Batch Culture Conditions for a mAb‑Producin…
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Online Ion Exchange Chromatography (IEX) Resource Hub—All in One Place
Are you an IEX-pert? If you use ion exchange chromatography, check out Cytiva's online IEX resource hub for useful information, from fundamentals to tips for advanced practitioners.
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Article
Scaling Up Novel Therapies
One way they do this, he says, is by “scaling out,” intensifying processes, for example by using fed-batch and perfusion on the upstream side, and multicolumn operations, whether it’s just higher cycl…
Article
Miniaturization to Become Even More Successful
Several talks focused on the use of miniaturized columns and screening plates, such as PreDictor 96-well plates and PreDictor RoboColumn™ units, and the possibility of these formats to become even mor…