Search results for "biopharm"
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Achieving Process Balance with Perfusion Bioreactors
With rising pressure to reduce costs and streamline bioprocess development, biopharmaceutical manufacturers are exploring the application of perfusion to a wider selection of biomolecules.
“Perfus…
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Using Multiple Techniques in Biosimilar Analysis
Application of multiple techniques at different conditions presents a more complete picture of a dynamic situation.
By Rebecca Strawn
Sergey/stock.adobe.com
Almost all drug product…
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Scaling Up Novel Therapies
Bioreactor scale-up
In more traditional biopharmaceutical development, bioreactors are typically the most difficult pieces of equipment to scale up, says Fredrik Lundström, product manager for…
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FDA Seeks to Enhance Manufacturing of Cell and Gene Therapies
FDA Seeks to Enhance Manufacturing of Cell and Gene Therapies
More consistent and reliable production processes are critical for advancing innovative treatments.
By Jill Wechsler
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Ensuring Viral Safety of Viral Vaccines and Vectors
To date, no infectious virus has been transmitted to a patient by a cell-line-derived biopharmaceutical. Extraneous vesiviruses, however, have recently appeared in bioreactors (2–5), and porcine circo…
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The Challenge of Disruptive Technologies in Bioprocessing
“When we look at the biologics market dynamics for treatment of diseases, certainly the increasing demand for biopharmaceuticals and the growing R&D expenditure in biopharma companies are factors driv…
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Optimizing Late-Stage and Commercial Cell-Culture Processes
Optimizing Late-Stage and Commercial Cell-Culture Processes
Late-stage and commercial biomanufacturing pose a challenge to cell-culture processing.
By Feliza Mirasol
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Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
This article highlights some of the significant changes in biopharmaceutical manufacturing (bioprocessing) that have occurred from 2003 to 2018. Most all of the changes in bioprocessing that have occu…
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CDMOs Driving Emerging Bio/Pharma Success
Analysts who track the industry expect 2018 to be the sixth straight year of substantial new investment in emerging biopharma companies from venture capital, public markets, and partnering. Funding fo…
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Putting Viral Clearance Capabilities to the Test
Viral clearance studies assess the capability of a downstream process to remove or inactivate potential contaminants and are based on a scale-down model of a biopharmaceutical production process. The …