Search results for " design"
Article
Moving Biosimilars Forward in a Hesitant Market
…lsewhere is automatically deemed to be interchangeable with its reference product, similar to the EU designation system. I think that would ease the burden,” Gabrielson says.
Easing the way for m…
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Benefits of DoE vs mechanistic modeling
Hear about the main differences between mechanistic modeling and design of experiments when used during chromatography process development. You will learn that, quite often, these methods work…
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Top Process Development Trends for 2022 and a Look into 2023
While this certificate-level interactive course on quality by design (QbD) covered fundamental concepts such as the principles of design space and establishing control strategies. Question-and-answer …
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Report from the 12th Plasma Product Biotechnology Forum
The program is focused on design and construction of new, standardized, and sustainable base fractionation facilities in Australia and Germany using optimized manufacturing processes and the latest te…
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Current Techniques and Challenges Presented in Scaling Between Bioreactors
cell culture
In this video, Andreas Castan, Strategic Technology Partnerships Leader at Cytiva, discusses the current techniques and challenges in scaling between bioreactors.
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Developing a Robust Bioprocess Using Mechanistic Models
Therefore, manufacturers have to design, implement and maintain measures to ensure that the bioprocess constantly delivers a high-quality product and patients are never at risk. The robustness of the …
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Implementing Inline Conditioning to Advance Process Intensification
When we started designing the new suite for large-scale manufacturing at our Cork site in Ireland, one of the biggest challenges was accommodating over 170,000 liters of buffers that is needed for the…
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Maximum Output Starts with Optimized Upstream Processing
The upstream capacity landscape does, however, vary largely with the product class, process design, and technology selection, notes Tania Pereira Chilima, deputy CTO of Univercells Technologies. She p…
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Bioreactors designs
Historically, STRs were adapted from the chemical industry to fit the needs of first the brewing and then the biopharmaceutical industry in order to enable the affordable indus…
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Innovative Chromatography Resins Can Improve Purity and Quality
To achieve this goal, Navigo created a unique technology (Precision Capturing) designed to generate target protein-specific affinity ligands. The engineered ligand is based on an artificial Protein A …