Search results for " design" in Articles / App Notes
Article
Current Techniques and Challenges Presented in Scaling Between Bioreactors
cell culture
In this video, Andreas Castan, Strategic Technology Partnerships Leader at Cytiva, discusses the current techniques and challenges in scaling between bioreactors.
…
Article
Developing a Robust Bioprocess Using Mechanistic Models
Therefore, manufacturers have to design, implement and maintain measures to ensure that the bioprocess constantly delivers a high-quality product and patients are never at risk. The robustness of the …
Article
Implementing Inline Conditioning to Advance Process Intensification
When we started designing the new suite for large-scale manufacturing at our Cork site in Ireland, one of the biggest challenges was accommodating over 170,000 liters of buffers that is needed for the…
Article
Maximum Output Starts with Optimized Upstream Processing
The upstream capacity landscape does, however, vary largely with the product class, process design, and technology selection, notes Tania Pereira Chilima, deputy CTO of Univercells Technologies. She p…
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Bioreactors designs
Historically, STRs were adapted from the chemical industry to fit the needs of first the brewing and then the biopharmaceutical industry in order to enable the affordable indus…
Article
Innovative Chromatography Resins Can Improve Purity and Quality
To achieve this goal, Navigo created a unique technology (Precision Capturing) designed to generate target protein-specific affinity ligands. The engineered ligand is based on an artificial Protein A …
Article
Genetic Vaccine Platforms Demonstrate Their Potential
In a pandemic, genetic vaccines offer several advantages over traditional approaches.
By Cynthia A. Challener
For a vaccine to be effective, the components of the disease o…
Article
Akron Bio Will Install a Cytiva FlexFactory to Manufacture Plasmid DNA
Cytiva and Akron will also work together on process design for pDNA production. Akron’s pDNA FlexFactory will be fully operational by the third quarter of 2021, the press release said.
“With thi…
Article
DiPIA online
Join on-demand presentations >>
Biacore surface plasmon resonance application specialists are eager to share their experience in assay design, validation, and data evaluation.
Article
Gene Therapies Push Viral Vector Production
This requires the design of a new process for each different serotype.” Chaudhary further explains that the presence of empty capsids presents yet another challenge associated with AAV vector purifica…