Search results for " resins"
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The Development and Application of a Monoclonal Antibody Purification Platform
A purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies.
The following ar…
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Alternative solutions to separate AAV full and empty capsids using anion exchange
Adeno-associated virus (AAV) is the main vector for gene therapy and there is need for scalable, cost-efficient, and robust chromatography-based purification. Key for a successful process are …
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Production of recombinant proteins using a novel affinity technology
This scientific paper from Journal of Chromatography A describes results of a study utilizing a Cytiva Protein Select™ affinity resin and tag platform to produce any recombinant proteins.
Re…
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Detailed agenda for Chromatography + filtration virtual summit
Explore the latest advancements in process development and scale-up
Check out the full agenda below!
Join Cytiva Chromatography and filtration summit online to learn from presentatio…
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Get Started: Purification of mAb Variants - eLearning
- Understand which resins are suitable for the first capture step.
- Discover the different strategies for removal of product- and process-related impurities in the polishing steps.
ACCESS TRAIN…
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Chromatography processes for the diversified therapeutic antibody pipeline
The diversity of antibody variants in today’s pipeline presents unique challenges for purification and we see molecules such as bsAbs, Fabs, dAbs, and others. Conventional chromatography protocols, …
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Top Process Development Trends for 2022 and a Look into 2023
Updates on purification advances continued in, “Enhancing Resins Addresses Purification Concerns,” which addresses purification concerns through advanced resin use.
Nuts-and bolts-detailed article…
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Dynamic Binding Capacity in Fiber-Based Chromatography
Just like with resins, the dynamic binding capacity (DBC) of a Fibro unit is affected by process conditions and by the properties of the target molecule. Thus, determining the DBC of a Fibro unit is s…
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Approaches to scaling up Chromatography Processes
Scaling up chromatography resins requires a thorough understanding of their intended use.
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Inspect Your Chromatography Column to Ensure You Get It Right
Read troubleshooting tips >>
Have you ever seen bubbles in the resin bed of your chromatography column? Or even space between the resin bed and the adaptor?
This is a sign that something …