Search results for " resins" in Articles / App Notes
Article
Purify App: Finding What You Need for Protein Purification
…nfigure an ÄKTA system to match your application?
Visit the NEW purify app to:
• select resins, prepacked columns, and empty columns
• configure and visualize ÄKTA systems in …
Article
Scaling Up Novel Therapies
One example Ransohoff cites is plate-based chromatography resin screening, enabled by technologies such as Cytiva Predictor plates, that allow users to consider binding properties of resins and soluti…
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Process Economy Simulations on a Protein A Capture Step
MabSelect PrismA is a next‐generation protein A chromatography resin that offers significantly enhanced alkaline stability and capacity compared with its predecessor products. This application note …
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
By Anurag Rathore, Vijesh Kumar
Among the various downstream processing unit operations that are used for purification of biotech products, chromatography is uniquely capable of providing resolu…
Article
Development of column packing methods based on pressure flow measurements
This paper provides a brief overview on the pressure-flow relationship for chromatography resins in packed and compressed beds, and the optimization of a suitable degree of bed compression when develo…
Article
High-Throughput Process Development in an Historical Environment
HTPD approaches in downstream goes beyond chromatography
The approaches in downstream process development, with screening of chromatography resins and parallel screening of optimal process conditi…
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Q&As with Industry Leaders
…
Jeanne Linke Northrop, BioPharm International
Emma Lind, Product Manager, Chromatography Resins, Cytiva
Optimizing your Cell Culture Process to Improve Productivity
Jeanne …
Article
Trends in Downstream Bioprocessing
These include, among many other new technology approaches identified in the study, the development of:
• Higher capacity resins
• Use of inline buffer dilution
• Use of inline conditioning…
Article
The Development and Application of a Monoclonal Antibody Purification Platform
A purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies.
The following ar…
Article
Alternative solutions to separate AAV full and empty capsids using anion exchange
Adeno-associated virus (AAV) is the main vector for gene therapy and there is need for scalable, cost-efficient, and robust chromatography-based purification. Key for a successful process are …