Search results for " capacity"
Article
Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
Manufacturing capacity issues have always been at the core of the annual survey, but as the industry has matured, the factors impacting capacity have become more complex.
This article highlight…
Article
A Look at the Affinity Chromatography Landscape
To meet this need, in 2017 the company developed a new Protein A ligand that offers both greater caustic stability (up to 1 molar sodium hydroxide) and increased binding capacity for monoclonal antibo…
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Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
This step often requires more optimization than initial capture and/or final polishing and aims to achieve high-dynamic binding capacity and maximum aggregate and host-cell protein (HCP) clearance. In…
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State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
of Rockville, MD, has surveyed developers of biotherapeutics and contract manufacturing organizations working in this space about current and projected capacity and production. The results, published …
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Process Chromatography: Continuous Optimization
Increased binding capacity can be achieved by changing the linker chemistry on the surface of the polymer so the ligands can be spaced equally in an optimized way, allowing more molecules to be attach…
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Improving Process-Scale Chromatography
“Recent chromatography developments have mostly focused on expanding the boundaries of capacity, especially in the area of Protein A resins, where few very high-capacity products exist. Capacity in a …
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CMOs Continue to Improve Overall Biomanufacturing Performance
Results from BioPlan Associates’ 12th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production (1) offer some clues as to what CMOs are doing to remain competitive.
CMOs…
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Trends in Downstream Bioprocessing
Although much of the discussion surrounding downstream purification concerns resolving or avoid short-term capacity constraints, the long-term implications to the industry are more crucial and signifi…
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Addressing the Challenges in Downstream Processing Today and Tomorrow
A significant consequence of the transfer of products between facilities is the generation of in-process pools that exceed the capacity of the storage vessels. Linking unit operations through tandem p…
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Industry Adoption of Single-Use Systems Remains Low
The market for single-use technology is growing, however, as capacity needs evolve.
Conservative attitude
Conservative attitudes tend to dominate the pharmaceutical and biop…