Search results for " capacity"
Article
Managing Biomanufacturing Capacity Expectations
Because executives commonly plan capacity requirements based on launch forecasts, there are many factors that can lead to miscalculations of capacity, making it challenging to know what capacity to bu…
Article
Cytiva Invests $500 Million Over 5 Years to Expand Global Capacity
13, 2020, Cytiva, announced that it is investing $500 million over five years to expand its global manufacturing capacity. The company will also hire nearly 1000 personnel in key areas as part of its …
Article
Innovation vs. Capacity: How CMOs Compete
In PharmSource’s update of the drug product manufacturing industry’s size and structure (1), the CMO industry was parsed into two strategic segments: innovation-driven CMOs and capacity-driven CMOs.
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Interpreting Protein Binding Capacities for Chromatography Resins
In this post, we explain what protein binding capacity is, how it can be measured, and what to look for on a manufacturer's specification sheet.
Article
Capacity and Performance of a Next Generation Protein A Chromatography Resin
The resin exhibits improved capacity over its predecessor MabSelect SuRe™ products, while maintaining purification performance. This application note demonstrates the binding capacity and purification…
Poster
Process economy and production capacity using single-use versus stainless steel fermentation equipment
In comparison with a stainless steel strategy, this study shows that the annual production capacity can be increased up to 100% with a single-use strategy due to a faster batch changeover procedure. T…
Article
How To Interpret Protein Binding Capacity: Chromatography Resins
Explore what protein binding capacity is, how it can be measured and what exactly to look for on a manufacturer’s specification sheet in this blog post.
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Article
How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins
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In protein purification, dynamic binding capacity (DBC) of a chromatography column describes the maximum amount of target protein that you can load onto your co…
Article
Determining and Optimizing Dynamic Binding Capacity
Dynamic binding capacity (DBC) indicates the quantity of a specific biomolecule that can be bound during a chromatography purification step under a specific set of process conditions. Determ…
Article
Dynamic Binding Capacity in Fiber-Based Chromatography
Just like with resins, the dynamic binding capacity (DBC) of a Fibro unit is affected by process conditions and by the properties of the target molecule. Thus, determining the DBC of a Fibro unit is s…