Search results for " Biacore"
Article
Understanding Protein Production from Start to Finish
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In protein research, going from idea to pure characterized protein takes multiple steps and techniques. Most scientists working with exploring proteins and developing spe…
Article
Life Science Online Training: Build Your Skills and Continue Your Education
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Cytiva continuously adds courses to cover a spectrum of life science topics such as chromatography and bioprocessing. You can find valuable course content for researc…
Article
Tips for Purifying and Analyzing Cryo-EM Samples
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Cryogenic electron microscopy (cryo-EM) provides possibilities to determine structures for more challenging proteins, such as membrane proteins and larger protein compl…
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Biacore SPR application specialists are eager to share their experience in assay design, validation, data evaluation.
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Article
Purifying Samples for Cryo-EM Preps
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Technical improvements in cryogenic electron microscopy (cryo-EM) have triggered a revolution in structural biology and made single-particle cryo-EM …
Article
Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …
Article
Getting it Right from the Start in the Drug Development Process
Proper process understanding allows researchers to critically identify factors that impact the drug substance and product as well as minimize or maintain them at approved levels. As a result, the de…
Article
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
…ocyte-colony stimulating factor (GCSF) to human CD114-R receptor (R&D systems) was determined by Biacore X100 plus biosensor (Cytiva). For GCSF-R affinity analysis, CD114-R receptor was immobilized o…
Article
Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…
Article
Using Multiple Techniques in Biosimilar Analysis
Application of multiple techniques at different conditions presents a more complete picture of a dynamic situation.
By Rebecca Strawn
Sergey/stock.adobe.com
Almost all drug product…