Search results for " Downstream PD" in Articles / App Notes
Article
Preparing for the Future: Visions and Insights for Biomanufacturing
The biopharmaceutical industry has a reputation of being averse to change. Yet, new market dynamics, such as growing competition from biosimilars and niche drugs targeting smaller patient populations,…
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Your Source of Information for Automated Multistep Protein Purification
Increasing the level of automation in protein purification can free up time and allow other tasks to be performed while the chromatography system is working. Cytiva has gathered recourses to support a…
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Generate an Automated Purification Protocol in Three Steps Using Predefined Methods
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If you are tied to your protein purification system during manual runs, learn how to get started with automated chromatography using predefined methods and add three…
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How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins
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In protein purification, dynamic binding capacity (DBC) of a chromatography column describes the maximum amount of target protein that you can load onto your co…
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Combining Purification Techniques in a Multistep Approach
Looking for a purification protocol to reach yield and target purity of your protein? Setting up a multistep purification might be the way forward for your lab.
With the right combination of dif…
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Integrated Semi-Continuous Process for mAb Production
A complete process for the production of a biopharmaceutical consists of a great number of distinct unit operations, for example, cell culture, filtration, and chromatography. Linking these differen…
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Queue Up Your Chromatography Steps
To save time and increase throughput, many scientists consider increasing the level of automation in their protein purification workflows. Learn how you can set up automated multi-step protocols uti…
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Selection Guide: Columns and Resins for Antibody Purification and Immunoprecipitation
Polyclonal antibodies, monoclonal antibodies (mAbs), and antibody fragments are usually purified by affinity chromatography. Resins containing an immobilized ligand (e.g., protein A, protein G, or p…
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Interpreting Protein Binding Capacities for Chromatography Resins
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Comparing the protein-binding capacities of resins from different suppliers is not straightforward because different methods may have been used and these methods are n…
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Gain Efficiency in Process Development
The development of efficient manufacturing processes is a necessity for cost-effective production of biopharmaceuticals. By carefully designing and evaluating your experiments, sufficient informatio…