Search results for " Downstream PD" in Articles / App Notes
Article
Web Chat June 19: Challenge Cytiva Scientists with Multistep Purification
Automated multistep (or multidimensional) protein purification is used to free up time, increase throughput, and reduce intermediate sample storage.
Join us for a free, one-hour web chat to dis…
Article
Optimization of Adenovirus Midstream Purification Steps
Adenovirus (AdV)-based vectors are widely evaluated as vaccine delivery system in preclinical and clinical studies for various infectious diseases. In this application note, studies of midstream pur…
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Cleaning Protein A Resins with 1 M NaOH
With increasing mAb titers, the impurity level of the cell culture feed increases. If not removed, these impurities can build up on the protein A resin and start to leach into the process material i…
Article
Chromatography Scale-Up: Don’t Get Tied Down by Bed Height
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When scaling, you can make better use of existing chromatography columns while avoiding overcapacity.
Keeping a constant residence time is a well-est…
Article
Capacity and Performance of a Next Generation Protein A Chromatography Resin
MabSelect™ PrismA is a protein A resin of which both the ligand and the base matrix have been optimized. The resin exhibits improved capacity over its predecessor MabSelect SuRe™ products, while maint…
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Going Viral
How a new factory-in-a-box is helping scale up manufacturing of viral vector-based therapies to reach more patients.
Manufacturing viral vector-based therapies such as vaccines and gene…
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Sanitization of ÄKTA™ pilot 600 Using Sodium Hydroxide
The ÄKTA pilot 600 chromatography system is designed to facilitate sanitization, with the high standards imposed by regulatory authorities for purity of the clinical products in mind. In this stu…
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Combine Chromatography Techniques: Get the Right Purity/Yield of Protein
This attractive wall poster shows you how to effectively combine techniques and succeed in your protein purification.
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Article
Your Protein Purification Questions Discussed
In one of Cytiva´s web chats, ÄKTA™ system users asked questions relating to lab-scale protein purification and ÄKTA systems, which experts answered during a live session.
The expert…
Article
Freedom to Roam During Protein Purification Runs
Have you ever felt tied to your ÄKTA system and itching to get out of the lab? Consider this scenario: You have started a run in the lab and want to get some work done in your office. You may …