Search results for " pharmaceutical"
Article
Optimization of Protein Expression in Escherichia Coli
May 01, 2015
By Siavash Bashiri, David Vikström, Nurzian Ismail
BioPharm International
Volume 28, Issue 5
Production of proteins for manufacturing therapeutics and pharmaceuticals is a c…
Article
Re-use of Protein A Resin: Fouling and Economics
30-40; Pharmaceutical Technology Europe, March (2003), pp. 45-56.
21. J. Moscariello, E. Lightfoot, and A. S. Rathore, BioPharm International 18 (8) (2005).
22. A. S. Rathore, S. Mittal, S. Lu…
Article
SEC in the Modern Downstream Purification Process
The simplicity of the separation mechanism and the power to separate large molecules or complexes from those smaller products or impurities not intended as an active pharmaceutical ingredient ensures …
Article
FDA Approves First Biosimilar
The approval is a groundbreaking decision, as Sandoz is the first pharmaceutical company to have a biosimilar product approved in the United States. Known as Zarzio outside of the US, Sandoz says its …
Article
The Bullish Outlook for Biosimilars
The cost of drugs has become a focal point of popular and industry dissatisfaction in the US, in spite of the relatively modest percentage of overall healthcare costs accounted for by pharmaceuticals …
Article
Fermentation for the Future
…uct can likely be purified more rapidly at lower cost and with the greatest chance for obtaining the pharmaceutical substance with its native conformation. “From a process perspective, soluble expres…
Article
Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
Stock, American Pharmaceutical Review (Oct. 1, 2010).
2. T. Kingsbury, BioProcess Int. 12 (4) 18-21 (2014).
3. H.F. Giles, E.M. Mount, and J.R. Wagner, The Definitive Processing Guide and Hand…
Article
Ligand-Binding Assays and the Determination of Biosimilarity
In October 2014, the American Association of Pharmaceutical Scientists (AAPS) Ligand-Binding Assay Bioanalytical Focus Group Biosimilars Action Program Committee published a whitepaper with recommenda…
Article
What Drove Biopharma Development in 2014?
As federal agencies continue to push for proof of quality in biologics, there is increased interest in, and use of, QbD in pharmaceutical development and that trend is only expected to rise. According…
Article
Mechanistic Modeling: Does it Have a Future in Process Development?
The application of mechanistic models for process development and optimization has been a topic of discussion in the pharmaceutical industry for many years. Mechanistic models are considered as an a…