Search results for " therapeutic" in Articles / App Notes
Article
2014 Manufacturing Trends and Outlook
About 20% said capacity was added due to the acquisition of another company or in-licensing of a drug product
Almost 45% of the respondents reported that their organizations manufacture therape…
Article
Determining Criticality-Process Parameters and Quality Attributes Part I: Criticality as a Continuum
Continuum of CQAs
Prior to the development of a new drug, companies frequently decide and document a therapeutic need in the marketplace for a new pharmaceutical. It is through this effort that th…
Article
Climate Change in Outsourcing
Announcements of plant and laboratory closures, layoffs, and narrowed therapeutic focus still occur almost monthly, and it doesn’t look like they will end any time soon.
In recent years, the globa…
Article
Trends in Downstream Bioprocessing
Downstream processing involves the recovery and purification of protein therapeutics for biopharmaceuticals, vaccines, and other biologics. It involves the removal of insoluble cell debris and parti…
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Operational Excellence: More Than Just Process Improvement
The pressures are many and relentless: price constraints, global competition, product complexity, and more challenging therapeutic areas. In response, many companies have embarked on operational excel…
Article
Report from the Eighth International Plasma Product Biotechnology Meeting Melia Salinas, Lanzarote, Spain
…s should be considered as a major risk reduction factor with respect to the safety of plasma derived therapeutic proteins.
Perhaps one of the next focus areas in product safety will be how to bet…
Article
A Platform Approach for the Purification of Domain Antibodies (Dabs)
This platform approach, based on a capture step with Capto L, enables increased efficiency and productivity in developing therapeutics based on Dabs.
Click here to download the application not…
Article
Milestones and Moderate Progress in 2012 Drug Approvals
The product is administered intramuscularly, and the resultant transduction of the surrounding muscle cells results in functional LPL expression, leading to an anticipated positive therapeutic outcome…
Article
Automated Concentration and Diafiltration of Multiple siRNA Samples
Controlled, systematic, quality small-interfering RNA (siRNA) production is the core of any successful RNA therapeutics program. To effectively screen potential targets for in vivo activity, it is nec…