Search results for " trends" in Articles / App Notes
Article
Regulatory Requirements for Safe and Efficient Biologic Drug Development
You think out of specs or even out of trends, how you're working on that. Look at your CMC section really in depth with a regulator's eye. Just think about stuff like that because those are the things…
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.
By: Pranav Vengsarkar and Nandu Deorkar
I…
Article
Implementation of Process Intensification Strategies Across the Entire Cell Culture Workflow
Andreas Castan, Strategic Technology Collaborations Leader at Cytiva, will discuss the latest trends across the industry in relation to process intensification and give specific examples of how both N…
Article
Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
Together, these trends have the potential to transform the industry, but advances in both instrumentation and lab informatics are needed before the full benefits can be realized.
With the exceptio…
Article
Scale-Up Model of a mAb Process from Microbioreactor to XDR-1000
All investigated bioreactor systems displayed similar trends over time and acceptable variability between cultures for viable cell density and viability profile, product titer, lactate, and product qu…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.
By Feliza Mirasol
ARTMOIS/STOCK.ADOBE.COM
Biopharmaceutical manufactu…
Article
Leveraging Computational Models of Glycosylation for Biopharma QA
Mantalaris, Trends Biotechnol. 37 (1) 9–16 (2019).
6. C. Kontoravdi and I.J. del Val, Curr. Opin. Chem. Eng. 22 89–97 (2018).
7. A.M. Goetze, et al., Glycobiology 21 (7) 949–959 (2011).
8.…
Article
Successfully Moving Regulated Data to the Cloud
In light of recent FDA guidance on data integrity, the challenges and benefits of using the public cloud to deploy and use data management software are discussed.
By Stuart Ward
…
Article
Nurturing Knowledge from Disparate Data Streams
There is also a focus on the application of machine learning and artificial intelligence in this area, letting machines identify trends and make observations that humans could probably find but don’t …
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Analytical exoglycosidases are transitioning from being largely academic tools to being s…