Search results for " development" in Articles / App Notes
Article
eBook: Purification of Antibody Therapeutics - Approach for Diversified Pipeline
Over the years, development beyond traditional monoclonal antibodies (mAbs) has increased. Today, we see multispecific and bispecific antibodies, antibody fragments, and antibody drug conjugates in th…
Article
Chromatography for the Diversified Antibody Pipeline
The antibodies have been there; however, we have also seen the development of fragments, conjugates, and bispecific antibodies. About 25 percent of the biopharmaceuticals are not pure antibodies they …
Article
Innovative Chromatography Resins Can Improve Purity and Quality
Ihre also notes that there continues to be strong demand for new mAbs to address new therapeutic areas and rising requests from customers of contract development and manufacturing organizations (CDMOs…
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How To Execute Successful Data Migrations
But that is exactly what they are, and as such, are no less deserving of meticulous planning, rigorous project management, and adherence to a software development lifecycle.
Migration projec…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
…s for commercial production, meaning that the same equipment and process conditions evaluated during development can be used for production, which simplifies technology transfer and reduces risk. Inc…
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Getting a Handle on Biopharma’s Most Critical Quality Attributes and Quality Control
…y-by-design (QbD) methods and process analytical technology (PAT) underpinnings to biopharmaceutical development and manufacturing. As Jose Menezes, CEO of 4Tune Engineering, pointed out in a white p…
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Nurturing Knowledge from Disparate Data Streams
This challenge is the greatest latent pain for development organizations,” Anderson asserts.
Volume and complexity
There will also always be challenges with getting the right data, acco…
Article
Modeling the Degradation of mAb Therapeutics
…evelopers to mitigate the risk of product degradation during the early stages of process and product development.
Proteins pose stability risks
Monoclonal antibodies are currently the leading…
Article
The Challenge of Disruptive Technologies in Bioprocessing
Driving innovation
Drivers behind the development of disruptive downstream technologies include increase in demand for biologics. Demand for mAbs, for example, is expected to increase by one or tw…
Article
Roadmap Leads to Innovative Biomanufacturing Strategies
…Bert Frohlich is an independent consultant who previously served as director of cell culture process development at Shire Pharmaceuticals.
Different perspectives
BioPharm: Why is it important …