Search results for " column"
Article
Analytical SEC: How Does Back Pressure Relate to Resolution?
High resolution in HPLC is not achieved by applying back pressure to the column. Let’s straighten out what really helps you achieve high-resolution analytical SEC data.
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Article
Protein Analysis with Size Exclusion Chromatography
This white paper presents fundamentals about analytical SEC and describes how our new-generation agarose-based SEC columns are used in analysis of biomolecules.
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Article
Reduce Hands-On Time in Your Ion Exchange Chromatography Runs
Optimization and improvements in ion exchange chromatography can be time consuming. Luckily, there are several tools that greatly facilitate this. Explore four valuable tips for reducing IEX hands-on …
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…cines
• Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
• Optimization of Fed‑Batch Culture Conditions for a mAb‑Produci…
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Online Ion Exchange Chromatography (IEX) Resource Hub—All in One Place
Are you an IEX-pert? If you use ion exchange chromatography, check out Cytiva's online IEX resource hub for useful information, from fundamentals to tips for advanced practitioners.
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Scaling Up Novel Therapies
Scaling Up Novel Therapies
Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies?
By Agnes S…
Article
Miniaturization to Become Even More Successful
Several talks focused on the use of miniaturized columns and screening plates, such as PreDictor 96-well plates and PreDictor RoboColumn™ units, and the possibility of these formats to become even mor…
Article
Understanding Validation and Technical Transfer, Part 2
Qualification protocols are used for process equipment, such as tanks, mills, piping systems, autoclaves, ion exchange units, chromatography columns, and stopper washers. Validation protocols are used…
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Gain Efficiency in Process Development
The development of efficient manufacturing processes is a necessity for cost-effective production of biopharmaceuticals. By carefully designing and evaluating your experiments, sufficient informatio…
Article
Putting Viral Clearance Capabilities to the Test
“In addition, expanded ranges of critical operating parameters may be evaluated, and column cleaning and carry-over must be evaluated.”
In testing prior to Phase III, Gilljam notes, “Reduction of …