Search results for " methods"
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Advances in Engineering of Protein-Based APIs
Advances in Engineering of Protein-Based APIs
New platform technologies, advanced modeling tools, and addressing patient needs are important developments.
By Cynthia A. Challener
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Ensure SEC Column Reproducibility in Protein Drug Analysis
Size exclusion chromatography (SEC) is the go-to analytical method in the analysis of therapeutic protein drugs. This article describes the factors affecting the reproducibility of columns and how you…
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State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
Despite diverse genetic-engineering methods and host organisms being available, industry has clearly come to prefer and standardize on use of mammalian systems, particularly CHO. Many more efficient o…
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Combining Purification Techniques in a Multistep Approach
With the right combination of different purification techniques, resins used, and how your methods are set up for a multistep approach, your protein purification will be successful in terms of either …
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The Challenge of Disruptive Technologies in Bioprocessing
Both methods would remove the challenge originating from practically limited column size or filter membrane area,” he states.
In addition, membrane absorbers have been suggested as a “disruptiv…
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Queue Up Your Chromatography Steps
To save time and increase throughput, many scientists consider increasing the level of automation in their protein purification workflows. Learn how you can set up automated multi-step protocols uti…
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Challenges in Cell Harvesting Prompt Enhancements
Challenges in Cell Harvesting Prompt Enhancements
Higher cell titers and cell densities have posed a challenge to cell harvesting, a crucial step in biologics manufacturing.
By Feliza Mi…
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Miniaturization to Become Even More Successful
The industry has turned to high-throughput process development (HTPD) methods—miniaturization, parallelization and automation in particular—to carry out the large number of experiments required for th…
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Understanding Validation and Technical Transfer, Part 2
Does the brewed coffee taste good? How will that be determined? Is it the same as the coffee chosen as a result of the taste testing? Are there any analytical methods that might provide confirmation? …
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Understanding Validation and Technical Transfer, Part 3
Understanding Validation and Technical Transfer, Part 3
Validation ensures safe and effective biologic products that benefit the patients whose health and wellbeing depend on the therapies. Part 1 |…