Search results for " cost"
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Single-Use and Continuous Processing Technologies Change Facility Design
Liquids can be pushed around in bags, thus removing the need for pipes and pumps, simplifying the facility and reducing engineering costs, for example. With stainless steel, duplicate equipment is nee…
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Defining Critical Quality Attributes for Monoclonal Antibody Therapeutic Products
An approach for establishing the CQAs of a mAb product by evaluating impact and uncertainty during risk assessment.
A critical quality attribute (CQA) has been defined as “a physical, chemical, …
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Concentrating Feed—an Applicable Approach to Improve Antibody Production
Feed-volume reduction can also reduce the cost of consumables, such as disposable bags and medium storage space. Because the feed dilutes the culture and reduces product concentration, the use of lowe…
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Biopharma Moves to Integrated, Single-Use, Downstream Processing
For those technologies that are available, she adds, scalability, performance, and cost are typical limitations.
Chromatography is the last purification unit operation to move to disposability and…
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Challenges in Analytical Method Development and Validation
…sitivity, range, robustness/maintenance, as well as speed and throughput capacity, but possibly also costs and ease of operations) should be established early and re-evaluated as needed throughout pr…
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Biopharma Takes a Nervous Glance Over Its Shoulder
According to the study findings, executives feel that US payers increasingly are not adequately valuing new treatments and are too focused on reducing prescription drug costs. This short-term approach…
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Novel Vaccine Technologies Meet the Need for Pandemic and Therapeutic Solutions
All of this testing extends the production time and increases the manufacturing cost.
Cell-culture technology
Cell-culture technology enables the use of raw materials that are readily ava…
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Q&A with Industry Leader Konstantin Konstantinov, Genzyme Vice-President
…turers to move to continuous processing, because it allows for more efficient operations and reduced costs.
These same drivers are present in biotechnology as well. In addition, continuous…
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Brazil Emerges as Global Biopharm Collaborator
With the economy still under control and regulation equivalent to those of developed nations, challenges now lie within high taxes and costs as well as strict price controls, according to Mussolini. S…
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Determining Criticality, Part Two: DoE and Data-Driven Criticality
The challenge faced by most development programs is how to efficiently and cost-effectively derive maximum process understanding in the fewest number of studies. To do this, a staged approach using mu…