Search results for " system" in Articles / App Notes
Article
Biomanufacturing: Demand for Continuous Bioprocessing Increasing
Sales of the leading alternating tangential flow (ATF) perfusion systems from leading suppliers, after more than 15 years, are under $20 million. And continuous processing downstream is still largely …
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The Evolving Role of Starting Materials in Cell and Gene Therapy
Apheresis center capacity, donor network access, sample handling expertise, and quality control systems all contribute to the ability to achieve reproducible starting material quality and efficacy.
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Cell-Culture Advances Test Bioreactor Performance Models
In addition, the information systems technology used has been validated and demonstrated to be cost effective, secure, compliant, and scalable with the volume of data generated from manufacturing proc…
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Science Focus Fuels Successful Process Development for Startups
These immunotherapies include Bria-IMT and Bria-OTS, which consist of cancer cell lines with the capability to directly present cancer antigens to the immune system and further stimulate the immune sy…
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Using Multiple Techniques in Biosimilar Analysis
While these are all good criterion for routine method selection, the techniques themselves are not necessarily aptly suited to specific molecules or systems.
Each molecule and/or formulation system…
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Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
Trends in adoption of diverse mammalian expression systems have also not materialized, as Chinese hamster ovary (CHO) cell lines have become the dominant expressions systems. In fact, nearly 80% of re…
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Understanding Validation and Technical Transfer, Part 2
While the example is not related to biopharmaceutical manufacture, it demonstrates various points to consider related to the inputs, the processing system, and the outputs that can be applied to bioph…
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Biopharma Says It Has an Evolution in New Technologies and Processes
Implementing automation technology can improve efficiency, help address the complexity of continuous processing, and assist in the challenge of training operators to run new systems. And, as more auto…
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Reconciling Sensor Communication Gaps
Single-use systems generally suffer from a “sensor gap” related to the need to balance measurement accuracy against the well-known benefits of single-use processing, including the avoidance of cleanin…
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Efforts Accelerate to Streamline Postapproval Change Process
By Jill Wechsler
Frequent revisions and updates in manufacturing processes and operations are routine after a drug comes to market to improve products and systems and ensure reliable supply of hig…