Search results for " continuous" in Articles / App Notes
Article
Developing a Continuous Large-Scale Prefusion Cell Culture Process
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Perfusion processes enable continuous operation over extended periods of time by constantly providing fresh nutrients for the cells and simultaneously removing …
Article
Robust Business Continuity Program Helps to Maintain Operations in the Face of Crisis
As we began 2020, no one could have foreseen that just a few weeks into the year, we would be facing a pandemic threatening unprecedented damage to human health and the world economy. Businesses are…
Article
CMOs Continue to Improve Overall Biomanufacturing Performance
Better process development is creating industry benchmarks for bioprocessing.
By Eric Langer
Biomanufacturing efficiency is on everyone’s minds, being the single most important area of focus…
Article
State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
What new areas did you explore in this year’s survey?
In 2018, and in recent years, we are seeing not just increased interest in and desires for adoption of continuous bioprocessing, but also expe…
Article
Technology Innovations Improve Process Chromatography Performance
Continuous chromatography
As continuous bioprocessing gains more attention, there is the need to evaluate whether current process chromatography technologies pose any limits or risks to implementi…
Article
Perfusion in the 21st Century
Now, improved continuous culture technologies such as perfusion are on the rise, as biosimilar manufacturers look for new ways to cut costs while increasing quality and productivity.
With perfusio…
Article
Digitalization: The Route to Biopharma 4.0
For dynamic inline pH adjustment in continuous processing, model-based control strategy has been employed by predicting the pH profile between the chromatography wash and the elution steps, thereby fa…
Article
Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
We also touch upon continuous versus batch manufacturing.
Topics covered include:
1:47 - Where the industry is headed with real-time analysis
3:17 - Scali…
Article
Improving Process-Scale Chromatography
…g use of automation, implementation of single-use technologies, and exploration of the potential for continuous chromatography at commercial scale are all impacting the development of large-scale chr…
Article
Trends in Single-use Bioreactors
Galliher (Cytiva): The latest innovations include higher-power microbial bioreactors, as well as improved capabilities for continuous perfusion. Single-use stirred-tank fermentation technology has bee…