Search results for "high-throughput" in Articles / App Notes
Article
Innovative Chromatography Resins Can Improve Purity and Quality
“Such improvements, combined with new tools, such as in-silico modeling of downstream processes and high-throughput screening of optimal process conditions at small scale, will enable a faster route t…
Article
Remote Monitoring and Big Data Advance Upstream Automation
In process development labs, for instance, he notes that the use of high-throughput culture systems such as the ambr15 and 250 from Sartorius have driven the need for automating sample handling and an…
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Process Development: 2020 Reflections and 2021 Possibilities
One efficient method is high-throughput process development (HTPD), which streamlines various bioprocess workflows to enable enhanced efficiency with parallelization and automation of experiments.
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Reimagining Affordable Biosimilars
…chniques allow simultaneous measurement of multiple product and process impurities in an automated, high-throughput mode. MS also offers an excellent orthogonal approach to traditional immunochemical…
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Highlights from the 5th International HTPD Conference, Part 3: Smart Process Development and a Look into the Future
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The high-throughput process development (HTPD) conference series is the key international forum for the presentation and discussion of topics relevant t…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
High-throughput techniques such as micro-bioreactor systems are another enabling technology, which, in combination with design of experiments (DoE) and multivariate data analysis (MVDA), support a qua…
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Best Practices for Selecting a Top-Quality Cell Line
“In some platforms with lower transfection efficiencies, identifying high-expressing cell clones depends upon screening tens of thousands of clones, which is achievable using flow cytometry and high-t…
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Free On-Demand Webinar: Smart Process Development of Chromatography Steps
Use of high-throughput methodologies
This toolset can help you overcome some of the challenges with time limitations, a diversified pipeline, and more regulatory demands for more comprehensive d…
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Addressing the Complex Nature of Downstream Processing with QbD
We have also developed many high-throughput tools applicable to process and product development within upstream, downstream formulations, and analytical development,” MacDonald says.
The benefits …
Article
Moving PAT from Concept to Reality
The ability to characterize proteins in a bioreactor on-line via a reliable, reproducible, rugged, high-precision, and high-throughput liquid chromatography–mass spectrometry (LC–MS) instrument at a c…