Search results for "Upstream"

Article Innovations in Cell Culture: Developing the Future
Join the discussion here >>  Thursday November 19, 2020 | 2:00 pm EST Developing an upstream cell culture process is hard work. Join this discussion to explore the costs versus b…

Article Implementation of Process Intensification Strategies Across the Entire Cell Culture Workflow
This presentation will describe strategies to intensify upstream operations. Andreas Castan, Strategic Technology Collaborations Leader at Cytiva, will discuss the latest trends across the indu…

Article Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
Current survey data continue to show that downstream operations still are struggling to keep up with improvements in upstream output, so downtime with upstream versus downstream equipment is normal. …

Article Industry Adoption of Single-Use Systems Remains Low
…ted to be around 20% in the past three years,” adds Parrish Galliher, chief technology officer of Upstream BioProcess at Cytiva’s Life Sciences division. Cost and time savings To date…

Article QbD Improves Cell-Culture Process Control
QbD Improves Cell-Culture Process Control A quality-by-design approach that implements PAT offers advantages in upstream cell-culture processing. By Feliza Mirasol Mar…

Article Single-use Bioreactors Have Reached the Big Time
…d meeting the growing expectations from our customers,” asserts Morgan Norris, general manager of upstream and cell culture with Cytiva. Whereas the first disposable bioreactors were ‘plastic’ co…

Article Mixing dynamics in a large volume single use mixer
Upstream applications such as medium  preparation and harvest require fast and efficient mixing whereas downstream mixing operations used in  purification and separation processes require sensitive mi…

Poster Modes of controlling charge variant distribution in Mab production
The characteristics of a biological drug, for example, charge variant profile, are determined to a large extent by the upstream expression system and conditions, but can also be influenced by the pu…

Article Trends in Single-use Bioreactors
In fact, we have sold a number of hybrid facilities with a combination of both single-use upstream and stainless steel systems. On the other hand, introducing a single-use bioreactor into a traditiona…

Article A Q&A With Parrish Galliher About Adopting Single-Use Systems
This week, Process Development Forum speaks with Parrish Galliher, Chief Technology Officer Upstream at Cytiva, about trends within the bioprocess area. What’s one of the biggest t…

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