Search results for " in silico" in Articles / App Notes
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Discovering the unknown: How does in silico process development change PD scientists’ work?
But what does it actually mean to perform process development in silico? Do I need to be a math expert? Where is modeling applicable? Will I not set foot in the lab ever again?
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In silico optimization of AAV full/empty particle separation with AIEX
We present a guiding workflow showcasing in silico process optimization of full and empty AAV5 particle separation on strong AEX resins, such as Capto™ Q ImpRes or Capto™ Q with GoSilico™ chromatograp…
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Accelerating CMC - The future of process development is in silico
Simulation for in silico process development is becoming a viable option to reduce the time needed for chemicals, manufacturing, and control (CMC) activities and increase process understanding. Advanc…
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In silico Approaches towards Automated Biomanufacturing
As part of manufacturing science and technology (MSAT), mechanistic modeling can be used to support several activities in biopharmaceutical production, including process transfer activities, in silico…
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Using Digital Twins to Model Process Chromatography
By Jennifer Markarian
A digital twin is a model of a process that allows process development experiments to be run in silico—on a computer—rather than on actual lab or manufacturing equipment. Alt…
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HTPD 2023 conference is coming up. What will be discussed and what happened last time?
The sessions guided by Cytiva modeling specialists will cover an introduction to the topic, benefits, and basic workflows of in silico process development and a deep dive into case studies and further…
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Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
6:50 - Key benefits of in silico process development driven by mechanistic models.
Visit cytiva.com/modeling for more information about mechanistic modeling.
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Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
After calibration, process parameters and the actual process set-up can easily be changed in silico without further experimentation. This opens a wide range of model applications—from early-stage proc…
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How to put mechanistic modeling into practice
Learn about insider recommendations to get started with in silico process development.
Check out our resources on good modeling practice, case studies, and other publications on mechanistic chromat…
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Report from the 6th International HTPD Conference
The sessions included an introduction to in silico process development and GoSilico™ Chromatography Modeling Software, covering the basic workflows of mechanistic modeling, a live software demo, but a…