Search results for " chromatography"
Poster
Evaluation of Protein A resin lifetime during extensive use (overloading) in continuous chromatography mode
In recent years, continuous chromatography has emerged as an alternative to batch operations to improve productivity or increase resin capacity utilization of chromatography purification processes. …
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Updated Ion Exchange Chromatography (IEX) Handbook
This handbook is an excellent resource on the topic of ion exchange chromatography, whether you are a first-time user or an expert.
Download the handbook.
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Using Xcellerex™ mixing system as a slurry tank when packing chromatography columns
The capability of the mixing system to keep the chromatography medium (resin) in suspension and the possibility to integrate the system in column packing were studied. Further, an evaluation of the ef…
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As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
For traditional mAbs, protein A chromatography is used to capture antibodies. Depending on the structure of the target antibody and the impurity profile, other affinities, like protein L or variants o…
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Choose your Optimal Wavelength for Chromatography
…For customers with a focus on emerging molecules, proteins, peptides and nucleic acid, ÄKTA pure™ chromatography system is flexible and intuitive, and includes the ability to upgrade as your res…
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Chromatography for the Diversified Antibody Pipeline
Jeanne Linke Northrop: How is the development we have seen in the antibody therapeutics area effecting chromatography capture that are used in antibody processing?
Eva Helding: The advantage…
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Sign-up to join Chromatography Virtual Summit 2022
Virtual event 15–17 November 2022
Join the Cytiva chromatography summit online to learn how you can make your chromatography process development smarter and faster!
Join presentations …
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New hydrophobic interaction chromatography (HIC) handbook
HIC is often used as a next step to purify proteins in high-salt conditions, for instance after ion exchange chromatography or ammonium sulfate precipitation. The role of this technique in protein pur…
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Adsorption isotherm models for chromatography
Indeed, in order to create a complete chromatography model, the adsorption of components within the adsorber beads needs to be considered. In this article we will discuss adsorption models for ion exc…
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Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
This structure allows high monoclonal antibody (mAb) binding capacities at very short residence times, which reduces cycle times to minutes instead of the hours needed for resin-based chromatography. …