Search results for " equipment" in Articles / App Notes
Article
Best Practices for Data Integrity
Best Practices for Data Integrity
Optimize practices and meet requirements using electronic data integrity systems.
By Jennifer Markarian
Maintainin…
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Contract Manufacturing Through the Years
Global bio/pharma companies have made more than $125 billion in capital expenditures for new plant and equipment in the past six years, much of it to support their biologics pipelines. Outsourcing of …
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The New World of Biopharmaceutical Manufacturing
Industry experts discuss the single-use revolution and changes to upstream and downstream processing equipment.
By Jennifer Markarian
…
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From Darwin to Recombinant Fc Multimers
R&D staff were then providing scientific support during equipment and process qualification, were involved in engineering batches to monitor manufacturing performance, and also contributed to the proc…
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Fusion Proteins Pose Manufacturability Challenges
Solutions for overcoming these issues are being developed in academia and the pharmaceutical industry by equipment vendors and drug companies alike.
Making proteins ‘druggable’
Many proteins…
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Single-use Bioreactors Have Reached the Big Time
“[Cytiva] is taking its experience in single-use bioreactor technologies for monoclonal antibody, recombinant protein, and vaccine processes and applying it in our Xuri line of cell therapy equipment …
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Reconciling Sensor Communication Gaps
Widespread familiarity with single-use equipment has greatly improved prospects for continuous unit operations and elevated “continuous” to official buzzword status. With continuous processing comes n…
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Impact of Manufacturing-Scale Freeze-Thaw Conditions on a mAb Solution
The objective of this study was to assess the impact of manufacturing-scale, freeze-thaw conditions on aggregation and subvisible particle formation of a monoclonal antibody solution (mAb-A; IgG1) u…
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Ensuring the Biological Integrity of Raw Materials
Thorough cleaning of equipment, testing, and review of material sources are also important steps to take. Bovine serum, for example, should be sourced from a country with a negligible risk of bovine s…
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Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
At larger scales, however, conventional chromatography, using stainless steel equipment, can still be a beneficial alternative. Here, we compare the performance of the disposable ReadyToProcess Adsorb…