Search results for " columns"
Article
Extractables Studies for Single Use Systems Used in ADC Manufacturing, Part 1
The low levels of extractables found in this study support the use of ReadyToProcess™ columns and ÄKTA™ ready Flow Kits in ADC processes.
Download the application note.
See Part 2 of th…
Article
Technology solutions simplifying chromatography unit operations
Chromatography operations typically involve steps such as resin slurry preparation, column packing, cleaning, unpacking, and resin storage. While each of the aforementioned steps can potentially be …
Article
Analysis of Glycosylation in Biosimilars
A step-wise process is used to characterize glycans and understand the functioning of a molecule for biosimilar development.
The structures of protein drugs such as monoclonal antibodies are mad…
Article
Maximize resin usage with continuous bioprocessing
The technology employs three or more chromatography columns to create a continuous purification step. In a PCC setup, columns are switched between the loading and nonloading steps, such as wash and el…
Poster
Unlocking the potential for efficiency in downstream bioprocesses
In today's bioprocessing industry, there is a demand to cut manufacturing costs while maintaining product safety and quality. Additionally, flexibility needs to be increased and time to market reduc…
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
If chromatography columns are used in the process flow, also specify the column volume and diameter required along with the desired number of cycles for each step.
Many single-use consumable suppl…
Article
Implications of Cell Culture Conditions on Protein Glycosylation
The authors present a review of the techniques commonly used for glycosylation analysis.
By Michiel E. Ultee, PhD, Dr. Richard Easton
This article reviews the implications of cell-culture co…
Article
Selecting the Right Viral Clearance Technology
By Cynthia Challener, PhD
The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug production that is well addressed by international regulatory requirements…
Article
Single-Use and Continuous Processing Technologies Change Facility Design
With no waiting for cell growth and cell-culture bioreactors continuously operating, columns can be smaller than when they need to handle whole fermenter volumes at one time. Ultimately, the whole fac…
Article
Biopharma Moves to Integrated, Single-Use, Downstream Processing
Suppliers see challenges to the adoption of single-use technologies for downstream processing as opportunities.
A lack of single-use technologies
The greatest barrier for adoption …