Search results for " techniques"
Article
Patenting Prospects for Cell-Based Therapies
Cell-based therapies are moving medical treatments forward, but intellectual property uncertainties may delay progress.
By Kevin Noonan
Treatment using cell-based therapies is a rapidl…
Article
Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
This week Process Development Forum talks about Protein A with Jonathan Royce, business leader for Cytiva chromatography resins.
mAb purification platforms are very well established, and …
Article
Bioburden Control in the Biopharmaceutical Industry
Attempts have been made to apply these techniques to the microbiological monitoring of water, air, and surfaces in the pharmaceutical industry (14-16).
Establishing Microbiological Contro…
Article
Column Selection Guide for ÄKTA Systems
Use this guide to facilitate your selection of prepacked chromatography columns.
The guide includes an overview table that shows compatibility of prepacked column formats and ÄKTA syst…
Article
The New World of Biopharmaceutical Manufacturing
Industry experts discuss the single-use revolution and changes to upstream and downstream processing equipment.
By Jennifer Markarian
…
Article
Hybrid Bioprocessing: A Q&A with Andrew Sinclair
The bias is toward fed batch with membrane techniques being used to increase cell density. Reduced media pricing would shift the balance toward perfusion-based processes.
The situation in downstrea…
Article
Unifying Continuous Biomanufacturing Operations
Although these drugs only exploit continuous techniques upstream, experience with this type of process upstream may help to eventually inform end-to-end manufacturing solutions. As the concept of inte…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
However, scale-up using these techniques is complicated and limited by the surface available for cell growth. One alternative is to scale up the production on microcarriers. Another solution is to us…
Article
Extractables Studies for Single Use Systems Used in ADC Manufacturing, Part 1
Extractable organic compounds and trace elements from the single‑use components were identified and semi‑quantitated with a complementary set of analytical techniques. The low levels of extractabl…
Article
Witnessing Major Growth in Next-Generation Antibodies
As mass spectrometry techniques have advanced in sensitivity over the years, researchers have the capability of pinpointing modifications to determine the location of conjugation sites for ADCs and en…